8-Carboxamidocyclazocine

id: 8-carboxamidocyclazocine-0-5605822
title: 8-Carboxamidocyclazocine
text: 8-Carboxamidocyclazocine (8-CAC) is an opioid analgesic drug related to cyclazocine, discovered by medicinal chemist Mark P. Wentland and co-workers in Cogswell Laboratory at Rensselaer Polytechnic Institute. Similarly to cyclazocine, 8-CAC acts as an agonist at both the μ- and κ-opioid receptors, but has a much longer duration of action than cyclazocine, and does not have μ antagonist activity. Unexpectedly, it was discovered that the phenolic hydroxyl group of cyclazocine could be replaced by
brand slug: wiki
category slug: encyclopedia
description: Opioid agonist drug
original url: https://en.wikipedia.org/wiki/8-Carboxamidocyclazocine
date created:
date modified: 2023-10-28T23:17:02Z
main entity: {"identifier":"Q4644264","url":"https://www.wikidata.org/entity/Q4644264"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/3/3a/8-Carboxamidocyclazocine.svg","width":975,"height":650}
fields total: 13
integrity: 15

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