AIR synthetase (FGAM cyclase)

id: air-synthetase-fgam-cyclase-284-17500064
title: AIR synthetase (FGAM cyclase)
text: Phosphoribosylformylglycinamidine cyclo-ligase is the fifth enzyme in the de novo synthesis of purine nucleotides. It catalyzes the reaction to form 5-aminoimidazole ribotide (AIR) from formylglycinamidine-ribonucleotide FGAM. This reaction closes the ring and produces a 5-membered imidazole ring of the purine nucleus (AIR): AIR synthetase catalyzes the transfer of the oxygen of the formyl group to phosphate. It is a sequential mechanism in which ATP binds first to the enzyme and ADP is released
brand slug: wiki
category slug: encyclopedia
description:
original url: https://en.wikipedia.org/wiki/AIR_synthetase_(FGAM_cyclase)
date created:
date modified: 2024-03-15T16:03:16Z
main entity: {"identifier":"Q4652000","url":"https://www.wikidata.org/entity/Q4652000"}
image:
fields total: 13
integrity: 13

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