Alpha secretase
id:
alpha-secretase-0-15087908
title:
Alpha secretase
text:
Alpha secretases are a family of proteolytic enzymes that cleave amyloid precursor protein (APP) in its transmembrane region. Specifically, alpha secretases cleave within the fragment that gives rise to the Alzheimer's disease-associated peptide amyloid beta when APP is instead processed by beta secretase and gamma secretase. The alpha-secretase pathway is the predominant APP processing pathway. Thus, alpha-secretase cleavage precludes amyloid beta formation and is considered to be part of the n
brand slug:
wiki
category slug:
encyclopedia
description:
Family of proteolytic enzymes
original url:
https://en.wikipedia.org/wiki/Alpha_secretase
date created:
date modified:
2024-03-27T09:57:00Z
main entity:
{"identifier":"Q908080","url":"https://www.wikidata.org/entity/Q908080"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/b/ba/APP_cleavage.png","width":1002,"height":578}
fields total:
13
integrity:
15