API5
id:
api5-284-14995569
title:
API5
text:
The human gene API5 encodes the protein Apoptosis inhibitor 5. This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of chemotherapeutic drugs. Crystal structure of API5 exhibited the function for protei
brand slug:
wiki
category slug:
encyclopedia
description:
Protein-coding gene in the species Homo sapiens
original url:
https://en.wikipedia.org/wiki/API5
date created:
date modified:
2023-12-01T03:07:48Z
main entity:
{"identifier":"Q18033085","url":"https://www.wikidata.org/entity/Q18033085"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/4/4e/Ideogram_human_chromosome_11.svg","width":474,"height":189}
fields total:
13
integrity:
15