Familial adenomatous polyposis
id:
familial-adenomatous-polyposis-260-16445553
title:
Familial adenomatous polyposis
text:
Familial adenomatous polyposis (FAP) is an autosomal dominant inherited condition in which numerous adenomatous polyps form mainly in the epithelium of the large intestine. While these polyps start out benign, malignant transformation into colon cancer occurs when they are left untreated. Three variants are known to exist, FAP and attenuated FAP are caused by APC gene defects on chromosome 5 while autosomal recessive FAP is caused by defects in the MUTYH gene on chromosome 1. Of the three, FAP i
brand slug:
wiki
category slug:
encyclopedia
description:
Pre-cancerous intestinal polyps
original url:
https://en.wikipedia.org/wiki/Familial_adenomatous_polyposis
date created:
date modified:
2024-01-27T16:45:47Z
main entity:
{"identifier":"Q1369011","url":"https://www.wikidata.org/entity/Q1369011"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/2/2b/Familial_adenomatous_polyposis_as_seen_on_sigmoidoscopy.jpg","width":521,"height":457}
fields total:
13
integrity:
15