Fluorothymidine F-18
id:
fluorothymidine-f-18-260-9829416
title:
Fluorothymidine F-18
text:
Fluorothymidine F-18 (FLT) is a tumor-specific PET tracer and radiopharmaceutical. It is an isotopologue of alovudine. FLT is suitable for monitoring how tumors respond to cytostatic therapy. FLT accumulates in proliferating cells where it indicates the activity of the enzyme thymidine kinase. Cell division can be characterized by the activity of that enzyme. FLT is phosphorylated as though it were thymidine, and is subsequently incorporated into DNA. Thymidine is essential for DNA replication.
brand slug:
wiki
category slug:
encyclopedia
description:
Chemical compound
original url:
https://en.wikipedia.org/wiki/Fluorothymidine_F-18
date created:
date modified:
2023-01-29T22:41:41Z
main entity:
{"identifier":"Q22908453","url":"https://www.wikidata.org/entity/Q22908453"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/6/66/3%27-fluoro-3%27-deoxythymidine.png","width":512,"height":577}
fields total:
13
integrity:
15