Fragment-based lead discovery

id: fragment-based-lead-discovery-260-5830860
title: Fragment-based lead discovery
text: Fragment-based lead discovery (FBLD) also known as fragment-based drug discovery (FBDD) is a method used for finding lead compounds as part of the drug discovery process. Fragments are small organic molecules which are small in size and low in molecular weight. It is based on identifying small chemical fragments, which may bind only weakly to the biological target, and then growing them or combining them to produce a lead with a higher affinity. FBLD can be compared with high-throughput screenin
brand slug: wiki
category slug: encyclopedia
description: Method used in drug discovery
original url: https://en.wikipedia.org/wiki/Fragment-based_lead_discovery
date created:
date modified: 2023-08-24T02:54:30Z
main entity: {"identifier":"Q8565284","url":"https://www.wikidata.org/entity/Q8565284"}
image:
fields total: 13
integrity: 14

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