Frakefamide

id: frakefamide-180-6760813
title: Frakefamide
text: Frakefamide (INN) is a synthetic, fluorinated linear tetrapeptide with the amino acid sequence Tyr-D-Ala-(p-F)Phe-Phe-NH2 which acts as a peripherally-specific, selective μ-opioid receptor agonist. Despite its inability to penetrate the blood-brain-barrier and enter the central nervous system, frakefamide has potent analgesic effects and, unlike centrally-acting opioids like morphine, does not produce respiratory depression, indicating that its antinociceptive effects are mediated by peripheral
brand slug: wiki
category slug: encyclopedia
description: Opioid agonist peptide compound
original url: https://en.wikipedia.org/wiki/Frakefamide
date created: 2012-04-27T17:44:33Z
date modified: 2024-09-05T09:40:29Z
main entity: {"identifier":"Q5477806","url":"https://www.wikidata.org/entity/Q5477806"}
image: {"content_url":"https://upload.wikimedia.org/wikipedia/commons/9/99/Frakefamide.svg","width":512,"height":331}
fields total: 13
integrity: 16

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