PITRM1
id:
pitrm1-284-15136341
title:
PITRM1
text:
Pitrilysin metallopeptidase 1 also known as presequence protease, mitochondrial (PreP) and metalloprotease 1 (MTP-1) is an enzyme that in humans is encoded by the PITRM1 gene. It is also sometimes called metalloprotease 1 (MP1).PreP facilitates proteostasis by utilizing an ~13300-A(3) catalytic chamber to degrade toxic peptides, including mitochondrial presequences and β-amyloid. Deficiency of PreP is found associated with Alzheimer's disease. Reduced levels of PreP via RNAi mediated knockdown h
brand slug:
wiki
category slug:
encyclopedia
description:
Protein-coding gene in humans
original url:
https://en.wikipedia.org/wiki/PITRM1
date created:
date modified:
2024-04-08T20:35:29Z
main entity:
{"identifier":"Q18035459","url":"https://www.wikidata.org/entity/Q18035459"}
image:
{"content_url":"https://upload.wikimedia.org/wikipedia/commons/2/2f/Ideogram_human_chromosome_10.svg","width":474,"height":189}
fields total:
13
integrity:
15